A 2013 study published in the Journal of Autism and Developmental Disorders revealed a possible link between the endocannabinoid system and immune cells in children with autism. CB2 receptors play a significant role in regulation of the immune system. As immune dysfunction is a factor that contributes to autism, the condition is believed to be linked to higher levels of CB2 receptors in cells (CB1 receptors, on the contrary, were not overexpressed). The authors of the study concluded that the use of cannabinoids and therapies that target CB2 receptors may be helpful for those who suffer from autistic disorders.
(Source: Siniscalco D. et al. “Cannabinoid receptor type 2, but not type 1, is up-regulated in peripheral blood mononuclear cells of children affected by autistic disorders.” J Autism Dev Disord. 2013 Nov;43(11):2686-95. doi: 10.1007/s10803-013-1824-9. https://www.ncbi.nlm.nih.gov/pubmed/23585028)